Sandbox 666: Difference between revisions

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* Two arms, which establish contacts with DNA backbones outside the recognition sequences.
* Two arms, which establish contacts with DNA backbones outside the recognition sequences.


This binding by the major groove is due to the position of scissile phosphodiester bonds.<ref>Recognition and cleavage of DNA by type-II restriction endonucleases, Pingoud A. & Jeltsch A. Eur.J.Biochem. 246,1-22 (1997)</ref>
This binding by the major groove is due to the position of scissile phosphodiester bonds.<ref name="A">Recognition and cleavage of DNA by type-II restriction endonucleases, Pingoud A. & Jeltsch A. Eur.J.Biochem. 246,1-22 (1997)</ref>


[[Image:Catalytic 1ERI.png | thumb | The catalytic core of Eco RI with the target DNA|left|400px]]
[[Image:Catalytic 1ERI.png | thumb | The catalytic core of Eco RI with the target DNA|left|400px]]