Sandbox 210: Difference between revisions
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Whereas CDKs are activated upon association with specific cyclins, the kinase activity of CDK5 is activated by its association with non-cyclin molecules such as p25, p35 or p39.<ref>doi:10.1038/371423a0</ref><ref>PMID:7592934</ref> | Whereas CDKs are activated upon association with specific cyclins, the kinase activity of CDK5 is activated by its association with non-cyclin molecules such as p25, p35 or p39.<ref>doi:10.1038/371423a0</ref><ref>PMID:7592934</ref> | ||
==Discovery of CDK5== | ==Discovery of CDK5== | ||
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==Structure== | ==Structure== | ||
The subunit of the CDK5 shares also a very similar three-dimensional (3D) structure with CDK2.<ref name="premier" /> | The subunit of the CDK5 shares also a very similar three-dimensional (3D) structure with CDK2.<ref name="premier">doi:10.1007/s00894-009-0629-4</ref> | ||
===Sequence similarities=== | ===Sequence similarities=== | ||
