Sandbox 213: Difference between revisions
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<Structure load='3CLN' size='300' frame='true' align='left' caption='Calcium-bound calmodulin' scene='Insert optional scene name here' /> | <Structure load='3CLN' size='300' frame='true' align='left' caption='Calcium-bound calmodulin' scene='Insert optional scene name here' /> | ||
[[Calmodulin]] (CaM) for Calcium-Modulated protein is an important protein that intervenes in a wide range of | [[Calmodulin]] (CaM) for Calcium-Modulated protein is an important protein that intervenes in a wide range of activities. | ||
CaM is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. | CaM is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. | ||
Calcium is an important mineral salt which represents 2% of body weight and 99% in teeth and bones. Calcium levels are finely regulated in the organism because it ediates and controls many biochemical processes, inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. That's why calmodulin is important for the regulation and finely transported in the body. | |||
Indeed,it is a small (16.7 kDa = 148 aa) and highly conserved protein that is necessary in all eukaryotic cells because it represents an essential calcium sensor with troponin C its isoform. ''' | Indeed,it is a small (16.7 kDa = 148 aa) and highly conserved protein that is necessary in all eukaryotic cells because it represents an essential calcium sensor with troponin C its isoform. ''' | ||