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==CRP, C-reactive Protein== | ==CRP, C-reactive Protein== | ||
The | The C Reactive Protein is a protein of acute phase, the first described, exclusively synthetized by the liver. | ||
The CRP was first isolated by Tillett and France in 1930, in patients' serum presenting an acute inflammation. This protein reacted to the polysaccharide C of the pneumocoque, ce qui lui valut son nom. [http://www.rndsystems.com/cb_detail_objectname_SU05_CReactiveProtein.aspx] | |||
The CRP contributes to innate host defense, and plays an important role in the inflammatory reactions. It can bind to specific molecular configurations typically exposed during cell death or found on the surfaces of pathogens. It is used as biological marker to reveal an inflammatory reaction and tissue damage. [http://biology.kenyon.edu/BMB/Chime2/2005/Jenny/FRAMES/] | |||
