4a92: Difference between revisions

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[[Image:4a92.jpg|left|200px]]
[[Image:4a92.png|left|200px]]


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Revision as of 05:42, 11 January 2012

File:4a92.png

Template:STRUCTURE 4a92

Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.

Template:ABSTRACT PUBMED 22160684

About this Structure

4a92 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  1. Schiering N, D'Arcy A, Villard F, Simic O, Kamke M, Monnet G, Hassiepen U, Svergun DI, Pulfer R, Eder J, Raman P, Bodendorf U. A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target. Proc Natl Acad Sci U S A. 2011 Dec 12. PMID:22160684 doi:10.1073/pnas.1110534108

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