InhA: Difference between revisions

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New page: ='''InhA'''= by Kelly Hrywkiw {{STRUCTURE_2h9i | PDB=2h9i | SCENE= }} __TOC__ =Introduction= The enzyme InhA is coded from the INHA gene that is similar in sequence to the ''[http...
 
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==The ACP family==
==The ACP family==


InhA can be further classified into the acyl carrier protein family(ACP's). These proteins generally all function in the transport of substrates in a myriad of pathways, such as: the synthesis of polypeptides and fatty acids<ref name ="Acyl Carrier Proteins">PMID:17012233</ref>.  Some examples of such proteins are listed below with links to their corresponding proteopedia page.
InhA can be further classified into the acyl carrier protein family(ACP's). These proteins generally all function in the transport of substrates in a myriad of pathways, such as: the synthesis of polypeptides and fatty acids<ref name ="Acyl Carrier Proteins">PMID:17012233</ref>.   
 
*[[3oic]] - FabL<br />
*[[1zhg]] - FabZ<br />
*[[3oig]] – BsENR I + NAD+INH<br />
*[[3oew]] - [[2x22]], [[2x23]], [[1eny]], [[1enz]] – MtENR+NAD – ''Mycobacterium tuberculosis''<br />
*[[2nsd]] – MtENR + NAD+piperidine derivative<br />
*[[1p44]] - MtENR + NAD+indole derivative<br />
*[[1bvr]] - MtENR + NAD + fatty-acyl substrate<br />
*[[2ntv]] - ENR+PTH-NAD – ''Mycobacterium leprae''<br />
*[[3oje]] – BcENR – ''Bacillus cereus''<br />
*[[3ojf]] – BcENR+NADP + indole naphthyrididone<br />
*[[2foi]] – PfENR fragment + diaryl ether inhibitor<br />
*[[2qio]] - ENR + NAD + TCL – ''Bacillus anthracis''<br />
*[[2p91]] – ENR – ''Aquifex aeolicus''<br />
*[[2pd3]] – HpENR+TCL – ''Helicobacter pylori''<br />
*[[1ve7]] – ApAARE + p-nitrophenyl phosphate<br />
*[[1i2z]] - EcENR + NAD + imidazole derivative<br />


''3D structures of ACP family''


[[Enoyl-Acyl-Protein Reductase
=Additional Resources=
=Additional Resources=
*[http://www.pdb.org/pdb/explore/explore.do?structureId=2H9I Mycobacterium tuberculosis InhA bound with ETH-NAD adduct, in the RCSB Protein Data Bank]
*[http://www.pdb.org/pdb/explore/explore.do?structureId=2H9I Mycobacterium tuberculosis InhA bound with ETH-NAD adduct, in the RCSB Protein Data Bank]
Retrieved from "https://proteopedia.org/InhA"