4dfu: Difference between revisions

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'''Unreleased structure'''
[[Image:4dfu.jpg|left|200px]]


The entry 4dfu is ON HOLD
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{{STRUCTURE_4dfu|  PDB=4dfu |  SCENE=  }}


Authors: Stogios, P.J., Dong, A., Evdokimova, E., Egorova, E., Di Leo, R., Li, H., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
===Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin===


Description: Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin
 
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{{ABSTRACT_PUBMED_22195561}}
 
==About this Structure==
[[4dfu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_casseliflavus Enterococcus casseliflavus] and [http://en.wikipedia.org/wiki/Streptomyces_kanamyceticus Streptomyces kanamyceticus]. This structure supersedes the now removed PDB entries  and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3r82 3r82]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DFU OCA].
 
==Reference==
<ref group="xtra">PMID:022195561</ref><references group="xtra"/>
[[Category: Enterococcus casseliflavus]]
[[Category: Streptomyces kanamyceticus]]
[[Category: Anderson, W F.]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Dong, A.]]
[[Category: Egorova, E.]]
[[Category: Evdokimova, E.]]
[[Category: Leo, R Di.]]
[[Category: Li, H.]]
[[Category: Minasov, G.]]
[[Category: Savchenko, A.]]
[[Category: Stogios, P J.]]
[[Category: Aminoglycoside phosphotransferase]]
[[Category: Aminoglycoside]]
[[Category: Antibotic]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Eukaryotic protein kinase-like fold]]
[[Category: Flavanoid]]
[[Category: Intracellular]]
[[Category: Kanamycin]]
[[Category: Kinase]]
[[Category: Quercetin]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase-antibiotic-inhibitor complex]]
[[Category: Transferase-antibotic-inhibitor complex]]

Revision as of 06:25, 8 February 2012

File:4dfu.jpg

Template:STRUCTURE 4dfu

Inhibition of an antibiotic resistance enzyme: crystal structure of aminoglycoside phosphotransferase APH(2")-ID/APH(2")-IVA in complex with kanamycin inhibited with quercetin

Template:ABSTRACT PUBMED 22195561

About this Structure

4dfu is a 2 chain structure with sequence from Enterococcus casseliflavus and Streptomyces kanamyceticus. This structure supersedes the now removed PDB entries and 3r82. Full crystallographic information is available from OCA.

Reference

  1. Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. A small molecule discrimination map of the antibiotic resistance kinome. Chem Biol. 2011 Dec 23;18(12):1591-601. PMID:22195561 doi:10.1016/j.chembiol.2011.10.018

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