4a5s: Difference between revisions

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'''Unreleased structure'''
[[Image:4a5s.jpg|left|200px]]


The entry 4a5s is ON HOLD
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{{STRUCTURE_4a5s|  PDB=4a5s |  SCENE=  }}


Authors: Ostermann, N., Kroemer, M., Zink, F., Gerhartz, B., Sutton, J.M., Clark, S.E., Dunsdon, S.J., Fenton, G., Fillmore, A., Harris, N.V., Higgs, C., Hurley, C.A., Krintel, S.L., MacKenzie, R.E., Duttaroy, A., Gangl, E., Maniara, W., Sedrani, R., Namoto, K., Sirockin, F., Trappe, J., Hassiepen, U., Baeschlin, D.K.
===CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR===


Description: CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR
 
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{{ABSTRACT_PUBMED_22177783}}
 
==About this Structure==
[[4a5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A5S OCA].
 
==Reference==
<ref group="xtra">PMID:022177783</ref><references group="xtra"/>
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Homo sapiens]]
[[Category: Baeschlin, D K.]]
[[Category: Clark, D E.]]
[[Category: Dunsdon, S J.]]
[[Category: Duttaroy, A.]]
[[Category: Fenton, G.]]
[[Category: Fillmore, A.]]
[[Category: Gangl, E.]]
[[Category: Gerhartz, B.]]
[[Category: Harris, N V.]]
[[Category: Hassiepen, U.]]
[[Category: Higgs, C.]]
[[Category: Hurley, C A.]]
[[Category: Krintel, S L.]]
[[Category: Kroemer, M.]]
[[Category: Mackenzie, R E.]]
[[Category: Maniara, W.]]
[[Category: Namoto, K.]]
[[Category: Ostermann, N.]]
[[Category: Sedrani, R.]]
[[Category: Sirockin, F.]]
[[Category: Sutton, J M.]]
[[Category: Trappe, J.]]
[[Category: Zink, F.]]
[[Category: Hydrolase]]
[[Category: Novartis compound nvp-biv988]]
[[Category: Type 2 diabetes]]

Revision as of 06:32, 8 February 2012

File:4a5s.jpg

Template:STRUCTURE 4a5s

CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR

Template:ABSTRACT PUBMED 22177783

About this Structure

4a5s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sutton JM, Clark DE, Dunsdon SJ, Fenton G, Fillmore A, Harris NV, Higgs C, Hurley CA, Krintel SL, Mackenzie RE, Duttaroy A, Gangl E, Maniara W, Sedrani R, Namoto K, Ostermann N, Gerhartz B, Sirockin F, Trappe J, Hassiepen U, Baeschlin DK. Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1464-8. Epub 2011 Nov 20. PMID:22177783 doi:10.1016/j.bmcl.2011.11.054

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