Large T Antigen: Difference between revisions

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=== Structures ===
== 3D structures  of large T antigen==


[[2ntc]] - Co-crystal structure of origin binding domain and DNA <br />
[[1faf]] – LTA N terminal – murine polyomavirus – NMR<BR />
[[1z1d]] - Structural model for interaction between large T antigen obd and RPA32 <br />
[[1n25]], [[1svo]] – SVLTA helicase domain – SV40<br />
[[2nl8]] - Co-crystal structure of obd and nonspecific palindromic oligonucleotide<br />
[[2fuf]] - SVLTA DNA-binding domain<br />
[[1tbd]] - SVLTA DNA-binding domain - NMR<BR />
[[2ipr]], [[2itj]], [[2if9]], [[3qn2]] - SVLTA origin-binding domain
 
===Large T antigen complex with DNA===
 
[[2itl]], [[2ntc]], [[3qk2]] - SVLTA origin-binding domain + DNA<br />
[[3qfq]] - LTA origin-binding domain + DNA – Merkel cell polyomavirus<br />
[[1svl]] - SVLTA helicase domain + ADP<br />
[[1svm]] - SVLTA helicase domain + ATP
 
===Large T antigen complex with protein===
 
[[1z1d]] – SVLTA origin-binding domain + replication protein A32 C terminal<br />
[[2h1l]] - SVLTA helicase domain + p53 DNA-binding domain<br />
[[1gh6]] – SVLTA + retinoblastoma protein
 
 
===Large T antigen peptide complex with protein===
 
[[1bk6]], [[1ejl]], [[1q1s]], [[1q1t]] – SVLTA peptide + karyopherin α


[[1svo]] - Unbound helicase domain <br />
[[1svl]] - Co-crystal structure of helicase and ADP <br />


[[2h1l]] - Complex of large T antigen and tumor suppressor p53 <br />


=== References ===
=== References ===
{{reflist}}
{{reflist}}
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