Elastase: Difference between revisions
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{{STRUCTURE_3ba0| PDB=3ba0 | SIZE=300| SCENE=Elastase/Cv/2 |right|CAPTION=Human Elastase (Metalloproteinase-12), [[3ba0]] }} | {{STRUCTURE_3ba0| PDB=3ba0 | SIZE=300| SCENE=Elastase/Cv/2 |right|CAPTION=Human Elastase (Metalloproteinase-12), [[3ba0]] }} | ||
[[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. The images at the left and at the right correspond to one representative elastase structure, ''i.e.'' the human Matrix Metalloproteinase-12 (MMP12), which is macrophage ELA ([[3ba0]]). Calcium ions are shown as green balls, zinc ions are grey balls and acetohydroxamic acid is shown as space filling object. | [[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. The images at the left and at the right correspond to one representative elastase structure, ''i.e.'' the human Matrix Metalloproteinase-12 (MMP12), which is macrophage ELA ([[3ba0]]). Calcium ions are shown as green balls, zinc ions are grey balls and acetohydroxamic acid is shown as space filling object. For additional details see [[Serine Proteases]]. | ||
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