4agw: Difference between revisions
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===Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases=== | |||
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{{ABSTRACT_PUBMED_20299508}} | |||
==About this Structure== | |||
[[4agw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:020299508</ref><references group="xtra"/> | |||
[[Category: Gallus gallus]] | |||
[[Category: Non-specific protein-tyrosine kinase]] | |||
[[Category: Choi, H G.]] | |||
[[Category: Gray, N.]] | |||
[[Category: Griffin, J D.]] | |||
[[Category: Seeliger, M.]] | |||
[[Category: Weisberg, E.]] | |||
[[Category: Atp-binding]] | |||
[[Category: Lipoprotein]] | |||
[[Category: Myristate]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Sh2 domain]] | |||
[[Category: Sh3 domain]] | |||
[[Category: Transferase]] | |||
Revision as of 06:41, 15 February 2012
Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases
Template:ABSTRACT PUBMED 20299508
About this Structure
4agw is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
- Weisberg E, Choi HG, Ray A, Barrett R, Zhang J, Sim T, Zhou W, Seeliger M, Cameron M, Azam M, Fletcher JA, Debiec-Rychter M, Mayeda M, Moreno D, Kung AL, Janne PA, Khosravi-Far R, Melo JV, Manley PW, Adamia S, Wu C, Gray N, Griffin JD. Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants. Blood. 2010 May 27;115(21):4206-16. Epub 2010 Mar 18. PMID:20299508 doi:10.1182/blood-2009-11-251751
