Response regulator: Difference between revisions

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'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments.
'''Response regulators''' (RR) are part of the two-component signal transduction systems which enable bacteria to sense and respond to a wide range of environments.
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR.  The RR act as phosphorylation-activated switches.  Most RR consist of N terminal shich is the signal receiving domain and C terminal which is the DNA-binding domain.  RR CheY is a chemotaxis  response regulator in bacteria.  RR Spo0 is the sporulation response regulator.  Details on response regulator PleD see [[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]]. For details on PhoP see [[PhoP Regulatory Domain]] and [[PhoP-PhoQ]]. For details on photosynthetic apparatus RR see [[PrrA in Rhodobacter sphaeroides]].
Two-component RR is a complex of histidine kinase (sensor protein SP) and RR.  The RR act as phosphorylation-activated switches.  Most RR consist of N terminal shich is the signal receiving domain and C terminal which is the DNA-binding domain.  RR CheY is a chemotaxis  response regulator in bacteria.  RR Spo0 is the sporulation response regulator.  For details see:<br />
[[PleD activation]], [[PleD allosteric product inhibition]], [[PleD catalysis]] - PleD.<br />
[[PhoP Regulatory Domain]] and [[PhoP-PhoQ]] - PhoP.<br />
[[PrrA in Rhodobacter sphaeroides]] - photosynthetic apparatus RR.<br />
[[WspR]] - WspR RR.




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[[3snk]] – RR – ''Mesorhizobium loti''<br/ >
[[3snk]] – RR – ''Mesorhizobium loti''<br/ >
[[3cg4]], [[3crn]] - RR receiver domain – ''Methanospirillum hungatei''<br/ >
[[3cg4]], [[3crn]] - RR receiver domain – ''Methanospirillum hungatei''<br/ >
[[3i42]] – RR receiver domain – ''Methylobacter flagellates''
[[3i42]] – RR receiver domain – ''Methylobacter flagellates''<br />
[[3bre]] – PaRR – ''Pseudomonas aeruginosa''<br/ >


===Unspecified RR receiver domain===
===Unspecified RR receiver domain===
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[[2zay]] – RR – ''Desulfuromonas acetoxidans''<br/ >
[[2zay]] – RR – ''Desulfuromonas acetoxidans''<br/ >
[[2rdm]] – RR (mutant) – ''Sinorhizobium medicae''<br/ >
[[2rdm]] – RR (mutant) – ''Sinorhizobium medicae''<br/ >
[[3bre]] – PaRR – ''Pseudomonas aeruginosa''<br/ >
[[3hdv]] – RR – ''Pseudomonas putida''<br/ >
[[3hdv]] – RR – ''Pseudomonas putida''<br/ >
[[3i5a]] – PsWspR – ''Pseudomonas syringae''<br/ >
[[3i5a]] – PsWspR – ''Pseudomonas syringae''<br/ >