DNA polymerase: Difference between revisions

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{{STRUCTURE_1taq| PDB=1taq | SIZE=400| SCENE=DNA_polymerase/Cv/1 |right|CAPTION=DNA polymerase complex with octylglucoside [[1taq]] }}

[[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand. Dpo sliding clamp is made of the complex of Dpo and [[Proliferating Cell Nuclear Antigen]] (PCNA) which encircles it. The BRCT domain in Dpo is the C-terminal domain of breast [[cancer]] susceptibility protein. The Klenow fragment is a large Dpo fragment produced upon cleavage of Dpo by [[Subtilisin|subtilisin]]. In the ''E. coli'', the EcDpo III subunits γ, δ, δ' are named clamp loader. This complex assembles the β subunit sliding clamp unto the DNA. '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions. '''Terminal deoxynucleotidyl transferase (TdT)''' is a Dpo expressed in immature lymphoid cells. TdT adds nucleotides to exons during antibody gene recombination. The images at the left and at the right correspond to one representative Dpo, ''i.e.'' the crystal structure of DNA polymerase I from ''Thermus aquaticus'' ([[1taq]]). For more details see [[DNA Polymerase I]].

[[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand. Dpo sliding clamp is made of the complex of Dpo and [[Proliferating Cell Nuclear Antigen]] (PCNA) which encircles it. The BRCT domain in Dpo is the C-terminal domain of breast [[cancer]] susceptibility protein. The Klenow fragment is a large Dpo fragment produced upon cleavage of Dpo by [[Subtilisin|subtilisin]]. In the ''E. coli'', the EcDpo III subunits γ, δ, δ' are named clamp loader. This complex assembles the β subunit sliding clamp unto the DNA. '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions. '''Terminal deoxynucleotidyl transferase (TdT)''' is a Dpo expressed in immature lymphoid cells. TdT adds nucleotides to exons during antibody gene recombination. The images at the left and at the right correspond to one representative Dpo, ''i.e.'' the crystal structure of DNA polymerase I from ''Thermus aquaticus'' ([[1taq]]). For more details see [[DNA Polymerase I]] and [[User:Karl E. Zahn/RB69 DNA polymerase (gp43)]].

DNA polymerase: Difference between revisions

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 {{STRUCTURE_1taq|  PDB=1taq  | SIZE=400| SCENE=DNA_polymerase/Cv/1 |right|CAPTION=DNA polymerase complex with octylglucoside [[1taq]] }}
-[[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand.  Dpo sliding clamp is made of the complex of Dpo and [[Proliferating Cell Nuclear Antigen]] (PCNA) which encircles it.   The BRCT domain in Dpo is the C-terminal domain of breast [[cancer]] susceptibility protein.  The Klenow fragment is a large Dpo fragment produced upon cleavage of Dpo by [[Subtilisin|subtilisin]].  In the ''E. coli'', the EcDpo III subunits γ, δ, δ' are named clamp loader.  This complex assembles the β subunit sliding clamp unto the DNA.  '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions.  '''Terminal deoxynucleotidyl transferase (TdT)''' is a Dpo expressed in immature lymphoid cells.  TdT adds nucleotides to exons during antibody gene recombination. The images at the left and at the right correspond to one representative Dpo, ''i.e.'' the crystal structure of DNA polymerase I from ''Thermus aquaticus'' ([[1taq]]).  For more details see [[DNA Polymerase I]].
+[[DNA polymerase]] '''(Dpo)''' reads a [[DNA|DNA strand]] and catalyzes the synthesis of its complementary strand.  Dpo sliding clamp is made of the complex of Dpo and [[Proliferating Cell Nuclear Antigen]] (PCNA) which encircles it.   The BRCT domain in Dpo is the C-terminal domain of breast [[cancer]] susceptibility protein.  The Klenow fragment is a large Dpo fragment produced upon cleavage of Dpo by [[Subtilisin|subtilisin]].  In the ''E. coli'', the EcDpo III subunits γ, δ, δ' are named clamp loader.  This complex assembles the β subunit sliding clamp unto the DNA.  '''Rev1''' is a '''Dpo''' involved in replication over DNA lesions.  '''Terminal deoxynucleotidyl transferase (TdT)''' is a Dpo expressed in immature lymphoid cells.  TdT adds nucleotides to exons during antibody gene recombination. The images at the left and at the right correspond to one representative Dpo, ''i.e.'' the crystal structure of DNA polymerase I from ''Thermus aquaticus'' ([[1taq]]).  For more details see [[DNA Polymerase I]] and [[User:Karl E. Zahn/RB69 DNA polymerase (gp43)]].
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