Sandbox Reserved 430: Difference between revisions
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The distortion to the structure of DNA caused by the cisplatin cross links allows the recognition of HMG domain protiens to bind to the DNA. | The distortion to the structure of DNA caused by the cisplatin cross links allows the recognition of HMG domain protiens to bind to the DNA. | ||
DNA containing platinum lesions show a shift from right handed B to left hand Z DNA | DNA containing platinum lesions show a shift from right handed B to left hand Z DNA | ||
A<scene name='Sandbox_Reserved_430/1a84_20_21/1'>kink</scene> | A<scene name='Sandbox_Reserved_430/1a84_20_21/1'>kink</scene> around the platinum coordination site (20,21) appears in green here. This is caused by the Cisplatin cross link. | ||
===Credits=== | ===Credits=== | ||
