Sandbox Reserved 425: Difference between revisions

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===Introduction===
===Introduction===
<scene name='Sandbox_Reserved_425/Test2/1'>test</scene>
-  COMT responsible for degradation of catchol neurotransmitters including DA
<scene name='Sandbox_Reserved_425/Test_2/1'>test 2</scene>
-  PD symptoms result from low levels of DA
-  inhibiting COMT has potential to treat PD in conjunction with L-DOPA (a DA precursor currently used to treat PD) by increasing the bioavailability and stability of L-DOPA
-  4PCM is a COMT inhibitor being studied to better understand inhibitor interactions with COMT in order to develop better inhibitors
        - carbonyl oxygen interacts with Trp143


===Overall Structure===
===Overall Structure===
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