Sandbox 35: Difference between revisions

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			This protease belongs to an extended family of aminopeptidases, dipeptidyl peptidases, endopeptidases, and other enzymes having both exo- and endo-peptidase activity. The inactivated zymogen with N-terminal propeptide regions - providing stability in alkaline environments and enabling proper folding - is activated through removal of the propeptide regions. <ref>PMID: 7845226</ref><ref>PMID: 12188906</ref> The protein is primarily secreted with its pro-region enabling transport from zymogen to lysosome through membrane association. <ref>PMID: 12188906</ref>
	This protease belongs to an extended family of aminopeptidases, dipeptidyl peptidases, endopeptidases, and other enzymes having both exo- and endo-peptidase activity. The inactivated zymogen with N-terminal propeptide regions - providing stability in alkaline environments and enabling proper folding - is activated through removal of the propeptide regions. <ref>PMID: 7845226</ref><ref>PMID: 12188906</ref>

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