3sgy: Difference between revisions
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===Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1006)=== | |||
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{{ABSTRACT_PUBMED_22347365}} | |||
==About this Structure== | |||
[[3sgy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGY OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022347365</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Anderson, A C.]] | |||
[[Category: Frey, K M.]] | |||
[[Category: Nadp]] | |||
[[Category: Nadph]] | |||
[[Category: One-carbon metabolism]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
Revision as of 05:48, 8 March 2012
Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1006)
Template:ABSTRACT PUBMED 22347365
About this Structure
3sgy is a 2 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
Reference
- Viswanathan K, Frey KM, Scocchera EW, Martin BD, Swain Iii PW, Alverson JB, Priestley ND, Anderson AC, Wright DL. Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes. PLoS One. 2012;7(2):e29434. Epub 2012 Feb 7. PMID:22347365 doi:10.1371/journal.pone.0029434
