1ftn: Difference between revisions
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New page: left|200px<br /> <applet load="1ftn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ftn, resolution 2.1Å" /> '''CRYSTAL STRUCTURE OF... |
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[[Image:1ftn. | [[Image:1ftn.jpg|left|200px]]<br /><applet load="1ftn" size="350" color="white" frame="true" align="right" spinBox="true" | ||
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caption="1ftn, resolution 2.1Å" /> | caption="1ftn, resolution 2.1Å" /> | ||
'''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''<br /> | '''CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
1FTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MG and GDP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | 1FTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FTN OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: small p-protein]] | [[Category: small p-protein]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 15:49:31 2008'' | ||
Revision as of 13:49, 15 February 2008
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CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Overview
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses, to extracellular signals. A 2.1 A resolution crystal structure of the, human RhoA-GDP complex shows unique stereochemistry in the switch I, region, which results in a novel mode of Mg2+ binding.
About this Structure
1FTN is a Single protein structure of sequence from Homo sapiens with MG and GDP as ligands. Full crystallographic information is available from OCA.
Reference
Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995
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