3mxf: Difference between revisions

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{{STRUCTURE_3mxf|  PDB=3mxf  |  SCENE=  }}  
{{STRUCTURE_3mxf|  PDB=3mxf  |  SCENE=  }}  


===Crystal Structure of the first bromodomain of humand BRD4 in complex with the inhibitor JQ1===
===Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1===




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==About this Structure==
==About this Structure==
[[3mxf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXF OCA].  
[[3mxf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXF OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20871596</ref><references group="xtra"/>
<ref group="xtra">PMID:020871596</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H.]]
[[Category: Bountra, C.]]
[[Category: Bountra, C.]]
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[[Category: SGC, Structural Genomics Consortium.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: Betsoff1]]
[[Category: Brd4]]
[[Category: Bromodomain containing protein 4]]
[[Category: Bromodomain-containing protein 4 isoform long]]
[[Category: Cap]]
[[Category: Cell cycle]]
[[Category: Hunk1]]
[[Category: Jq1]]
[[Category: Mcap]]
[[Category: Mitotic chromosome associated protein]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]

Revision as of 06:56, 28 March 2012

File:3mxf.png

Template:STRUCTURE 3mxf

Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1

Template:ABSTRACT PUBMED 20871596

About this Structure

3mxf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Selective inhibition of BET bromodomains. Nature. 2010 Sep 24. PMID:20871596 doi:10.1038/nature09504

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