Lipase: Difference between revisions

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== '''Protein - Substrate Interactions''' ==
== '''Protein - Substrate Interactions''' ==


Lipase binds <scene name='Lipase/Substrate_contacts/1'>substrates such as cholesteryl linoleate</scene> with numerous hydrophobic contacts.  Seen here is the Candida rugosa lipase in
Lipase binds <scene name='Lipase/Substrate_contacts/1'>substrates such as cholesteryl linoleate</scene> with numerous hydrophobic contacts.  As is seen here the Candida rugosa lipase interacts with the alkyl group of cholesteryl linoleate via a hydrophobic rift within the protein.  This rift orients the molecule to optimize the lipolysis reaction. 
<scene name='Lipase/Complex_2/1'>complex</scene> with two molecules of cholesteryl linoleate (grey).
<scene name='Lipase/Complex_2/1'>complex</scene> with two molecules of cholesteryl linoleate (grey).