Papain: Difference between revisions
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[[Image:papayas.jpg|300px|right|thumb|Papaya<ref>http://dailyfitnessmagz.com/2011/03/papayas-nutrition-facts/</ref> | [[Image:papayas.jpg|300px|right|thumb|Papaya<ref name="Papaya Fun Facts">http://dailyfitnessmagz.com/2011/03/papayas-nutrition-facts/</ref> | ||
'''Papain''' belongs to an extended family of aminopeptidases, dipeptidyl peptidases, endopeptidases, and other enzymes having both exo- and endo-peptidase activity. The inactivated zymogen with N-terminal propeptide regions - providing stability in alkaline environments and enabling proper folding - is activated through removal of the propeptide regions. <ref>PMID: 7845226</ref> The protein is primarily secreted with its pro-region enabling transport from zymogen to lysosome through membrane association and mediation. <ref>PMID: 12188906</ref> | '''Papain''' belongs to an extended family of aminopeptidases, dipeptidyl peptidases, endopeptidases, and other enzymes having both exo- and endo-peptidase activity. The inactivated zymogen with N-terminal propeptide regions - providing stability in alkaline environments and enabling proper folding - is activated through removal of the propeptide regions. <ref>PMID: 7845226</ref> The protein is primarily secreted with its pro-region enabling transport from zymogen to lysosome through membrane association and mediation. <ref>PMID: 12188906</ref> | ||
