Sandbox Reserved 489: Difference between revisions
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Post translational modifications of renin include; precursor cleavage of propetide to produce active mature renin, disulfide bond formation, and glycosylation of certain residues. Disulfide bonds are form to connect serine residues <scene name='Sandbox_Reserved_489/Disulfidebond1/1'>51 to 58</scene>, <scene name='Sandbox_Reserved_489/Disulfidebond2/1'>217 to 221</scene>, and <scene name='Sandbox_Reserved_489/Disulfidebond3/1'>259 to 296</scene>. <scene name='Sandbox_Reserved_489/Glycosylated/1'>Two asparagine residues</scene> at positions 15 and 75 are glycosylated in the mature and active renin. | Post translational modifications of renin include; precursor cleavage of propetide to produce active mature renin, disulfide bond formation, and glycosylation of certain residues. Disulfide bonds are form to connect serine residues <scene name='Sandbox_Reserved_489/Disulfidebond1/1'>51 to 58</scene>, <scene name='Sandbox_Reserved_489/Disulfidebond2/1'>217 to 221</scene>, and <scene name='Sandbox_Reserved_489/Disulfidebond3/1'>259 to 296</scene>. <scene name='Sandbox_Reserved_489/Glycosylated/1'>Two asparagine residues</scene> at positions 15 and 75 are glycosylated in the mature and active renin. | ||
==Function== | |||
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Renin secretion is stimulated by a decrease in arterial blood pressure, a decrease in sodium chloride levels in kidney [http://en.wikipedia.org/wiki/Nephron nephrons], or [http://en.wikipedia.org/wiki/Sympathetic_nervous_system sympathetic nervous system] activity. | |||
