Sandbox Reserved 489: Difference between revisions
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<span style="font-size:200%">Renin</span> | <span style="font-size:200%">Renin</span> | ||
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[[Image:2RenCartoon.png|Renin]] | |||
Renin, also known as angiotensinogenase, is an aspartyl protease and belongs to the protein family peptidase A1. Aspartyl proteases are endopeptidases that typically use two aspartate residues in the active site in a reduction-oxidation reaction with water to specifically cleave peptide substrates. Mature renin circulates in the blood and contains 340 amino acid residues and has a mass of approximately 37 kDa. The function of renin is to cleave the angiotensin I precursor, angiotensinogen, to produce angiotensin I. | Renin, also known as angiotensinogenase, is an aspartyl protease and belongs to the protein family peptidase A1. Aspartyl proteases are endopeptidases that typically use two aspartate residues in the active site in a reduction-oxidation reaction with water to specifically cleave peptide substrates. Mature renin circulates in the blood and contains 340 amino acid residues and has a mass of approximately 37 kDa. The function of renin is to cleave the angiotensin I precursor, angiotensinogen, to produce angiotensin I. | ||
