Multiple sclerosis: Difference between revisions
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===Monoclonal Antibodies=== | ===Monoclonal Antibodies=== | ||
'''Monoclonal antibodies''' have been studied since the 1980s and a great deal is known about them. There are three different types that are differentiated by their structural similarity to human antibody structure. Humanized antibodies have more than 90% human components with the rest being murine. These include natalizumab, alemtuzumab, and daclizumab. Rituximab is a chimeric antibody, which contain at least 66% human sequence and structure. Monoclonal antibodies have specific targets and as such have varying mechanisms of binding, blocking, or signaling. | |||
===Cytotoxic and Other Agents=== | ===Cytotoxic and Other Agents=== | ||
==References== | ==References== | ||