Multiple sclerosis: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 47: Line 47:


===Monoclonal Antibodies===
===Monoclonal Antibodies===
Natalizumab, Alemtuzumab, Rituximab, Daclizumab.
 
'''Monoclonal antibodies''' have been studied since the 1980s and a great deal is known about them. There are three different types that are differentiated by their structural similarity to human antibody structure. Humanized antibodies have more than 90% human components with the rest being murine. These include natalizumab, alemtuzumab, and daclizumab. Rituximab is a chimeric antibody, which contain at least 66% human sequence and structure. Monoclonal antibodies have specific targets and as such have varying mechanisms of binding, blocking, or signaling.  
 
===Cytotoxic and Other Agents===
===Cytotoxic and Other Agents===
==References==  
==References==