Sandbox Reserved 479: Difference between revisions
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Myosin plays a role in the universal mechanism known as the actinomysin chemomechanical cycle. Actin binds and releases myosin, causing the myosin lever to interact and relax in a cyclic manner.<ref name="Varkuti" /> | Myosin plays a role in the universal mechanism known as the actinomysin chemomechanical cycle. Actin binds and releases myosin, causing the myosin lever to interact and relax in a cyclic manner.<ref name="Varkuti" /> | ||
# ATP binds to S1 causing Actin to disassociate out of it's rigor complex (between actin and the S1 catalytic site on myosin) | |||
# S1 causes the hydolysis of ATP to ADP and Pi | |||
# Actin interacts with the S1-ADP-Pi complex and Pi is released | |||
# S1 catalytic site's affinity for actin increases and the Actin-S1-ADP forms | |||
# ADP is released, causing them to again enter into the tightly bound rigor complex | |||
==Medical Implications or Possible Applications== | ==Medical Implications or Possible Applications== | ||
