Sandbox Reserved 479: Difference between revisions
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====Ligands==== | ====Ligands==== | ||
====X-Ray Diffraction==== | ====X-Ray Crystallography and Diffraction==== | ||
It was not until recently that crystal structures could be used to analyze myosin and it's role in the actinomysin chemomechanical cycle. X-ray diffraction studies have been conducted on whole muscles and muscle fibers to learn how structural changes promote and facilitate motor activity. Movement of myosin was analyzed under near physiological conditions using modern synchrotron radiation sources. Structural alterations were created through use of unique time and spatial resolution. Snychrotron radiation generates a monochromatic X-ray breams of diameter 0.2-0.3 mm, similar to that of the muscle fiber. So, high resolution images and video of a single muscle cell are possible.<ref name="Koubassova">PMID: 22339600</ref> | It was not until recently that crystal structures could be used to analyze myosin and it's role in the actinomysin chemomechanical cycle. X-ray diffraction studies have been conducted on whole muscles and muscle fibers to learn how structural changes promote and facilitate motor activity. Movement of myosin was analyzed under near physiological conditions using modern synchrotron radiation sources. Structural alterations were created through use of unique time and spatial resolution. Snychrotron radiation generates a monochromatic X-ray breams of diameter 0.2-0.3 mm, similar to that of the muscle fiber. So, high resolution images and video of a single muscle cell are possible.<ref name="Koubassova">PMID: 22339600</ref> | ||
