Sandbox Reserved 479: Difference between revisions
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==Structure== | ==Structure== | ||
Myosin is a 520 kDa hexamer (6 subunit) structure. It has two heavy chains (weighing 220 kDa each) and 4 light chains (weighing 20 kDa each.<ref name="CHEM43">[http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Myosin/STRUCT~1.HTM]</ref> | Myosin is a 520 kDa hexamer (6 subunit) structure. It has two heavy chains (weighing 220 kDa each) and 4 light chains (weighing 20 kDa each).<ref name="CHEM43">[http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Myosin/STRUCT~1.HTM]</ref> | ||
====Oligomeric State==== | ====Oligomeric State==== | ||
====Secondary Structure==== | ====Secondary Structure==== | ||
The N-terminal comprises a globular head in the heavy chains, and the C-terminal ends with an alpha helix. The globular head region is also known as S1, and also contains mostly alpha-helices that are critical to maintaining structure. The C-terminal end contains interspersed hydrophobic regions that give rise to a "coiled coil" structure.<ref name="CHEM43" /> | |||
====Active Site==== | ====Active Site==== | ||
