Sandbox Reserved 496: Difference between revisions
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'''Cholix Toxin''' named also CT, is a protein toxin that uses ADP-ribosyltransferases to modify target proteins in human cells. The mono-ADP-ribosyltransferase toxins are bacterial virulence factors that are believed to be a factor in many disease states in animals plants as well even humans. For a list of various and other similar toxins see [[Toxins]]. | '''Cholix Toxin''' named also CT, is a protein toxin that uses ADP-ribosyltransferases to modify target proteins in human cells. The mono-ADP-ribosyltransferase toxins are bacterial virulence factors that are believed to be a factor in many disease states in animals plants as well even humans. For a list of various and other similar toxins see [[Toxins]]. | ||
<Structure load=' | <Structure load='569B' size='300' color='white' frame='true' align='right' caption='testcaption' /> | ||
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== Cholix Toxin from ''Vibrio Cholerae ''== | == Cholix Toxin from ''Vibrio Cholerae ''== | ||
The [http://en.wikipedia.org/wiki/Crystal_structure crystal structure] of the [http://en.wikipedia.org/wiki/Proteolysis proteolytically] activated monomeric form of Cyt2Ba was determined at | The [http://en.wikipedia.org/wiki/Crystal_structure crystal structure] of the [http://en.wikipedia.org/wiki/Proteolysis proteolytically] activated monomeric form of Cyt2Ba was determined at 2.1Å resolution. It consists of a single domain of <scene name='Cyt2Ba/Alpha_beta/5'>α/β</scene> architecture with a <scene name='Cyt2Ba/Beta/2'>β-sheet</scene> (yellow) surrounded by 2 <scene name='Cyt2Ba/Alpha/2'>α-helical</scene> layers <font color='red'><b>(red)</b></font> forming a cytolysin fold. | ||
