Sandbox Reserved 475: Difference between revisions

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== ACETYLCHOLINE RECEPTOR ==
== ACETYLCHOLINE RECEPTOR ==
<Structure load='2bg9' size='400' frame='true' align='right'
<Structure load='2bg9' size='400' frame='true' align='right'
caption='Refined nicotinic receptor structure at 4.0 &Aring; [[resolution]] ([[2ypi]]). 5 chain structure of Ion channels with sequence from Torpedo marmorata.
caption='Refined nicotinic receptor structure at 4.0 &Aring; resolution ([[2bg9]]). 5 chain structure of Ion channels with sequence from Torpedo marmorata.' scene='' />
scene='' />
 
'''Nicotinic Acetylcholine Receptor''' (nAChRs) is a neurotransmitter receptor also known as a specialized integral membrane protein. Acetylcholine receptor proteins reside as ligand-gated ion channels on the motor end plate of the postsynaptic cleft in the neuromuscular junction. Nicotinic acetylcholine receptors are responsible for the regulation of sodium (Na+) ion concentration entering and potassium (K+) ion concentration leaving the muscular cytosol, ultimately resulting in an action potential from the differences in electrochemical gradients.