Formate dehydrogenase: Difference between revisions
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'''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe4S4 center and then to cytochrome. The Mo-dependent FDH-H from E. coli contains SelCys | '''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either NAD+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe4S4 center and then to cytochrome. The Mo-dependent FDH-H from E. coli contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe4S4. | ||
==3D structure of formate dehydrogenase== | ==3D structure of formate dehydrogenase== | ||
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[[2fss]] – CbFDH – ''Candida boidinii''<BR /> | [[2fss]] – CbFDH – ''Candida boidinii''<BR /> | ||
[[2j6i]] – CbFDH C terminal (mutant) <BR /> | [[2j6i]] – CbFDH C terminal (mutant) <BR /> | ||
[[3fn4]] - MoFDH – Moraxella<BR /> | [[3fn4]] - MoFDH – ''Moraxella''<BR /> | ||
[[3naq]], [[3jtm]] – ArFDH – ''Arabidopsis thaliana''<BR /> | [[3naq]], [[3jtm]] – ArFDH – ''Arabidopsis thaliana''<BR /> | ||
[[2nad]] – PsFDH + NAD<BR /> | [[2nad]] – PsFDH + NAD<BR /> | ||
