Sandbox Reserved 475: Difference between revisions

'''nAChRs''' as an ionotropic receptor, which are in direct facilitation of ion movement. When a ligand binds to the active site of the receptor, the channel responds by opening. Likewise, when the ligand is removed the channel closes. They are activated by the binding of the acetylcholine neurotransmitter. Once the receptor is activated the ion channel opens allowing the exchange of salt ions. Nicotinic acetylcholine receptors are responsible for the regulation of sodium (Na+) ion concentration entering and potassium (K+) ion concentration leaving the muscular cytosol, ultimately resulting in an action potential from the differences in electrochemical gradients.