Sandbox Reserved 475: Difference between revisions
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=== Drugs and Toxins === | === Drugs and Toxins === | ||
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'''nAChRs''' are the target sites of by many toxins such as those present in snake venom such as α-bungarotoxin. These receptors can also be blocked by curare, hexamethonium as well as neuromuscular blocking agents such as those used in medical anesthesia. Neuromuscular blocking agents bind reversibly to nicotinic receptors in the neuromuscular junction. | '''nAChRs''' are the target sites of by many toxins such as those present in snake venom such as α-bungarotoxin.<ref>Samson, A. O.; Levitt, M. (2008). "Inhibition Mechanism of the Acetylcholine Receptor by α-Neurotoxins as Revealed by Normal-Mode Dynamics". Biochemistry 47 (13): 4065–4070.</ref> These receptors can also be blocked by curare, hexamethonium as well as neuromuscular blocking agents such as those used in medical anesthesia. Neuromuscular blocking agents bind reversibly to nicotinic receptors in the neuromuscular junction. | ||
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