Sandbox Reserved 460: Difference between revisions

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==='''Nitrite Reductase'''===

Nitrite reductase is an enzyme that belongs to the Oxidoreductase family for catalyzing the six-electron reduction of nitrite into ammonia, using the reduced ferredoxin as the electron donor. It is a monomeric protein with molecular mass near 66 kDa characterized by a unique active site which contains a single <scene name='Sandbox_Reserved_460/Active_site/1'>[4Fe-4S] cluster</scene> and a single siroheme (which serves as the binding site for nitrite) via a bridging sulfur atom from a cysteine residue. The protein has a globular fold consisting of 3 alpha/beta domains with the siroheme-iron sulfur cofactor at the interface of the three domains. The siroheme is surrounded by several ionizable amino acid residues that facilitate the binding and subsequent reduction of nitrite.