Sandbox Reserved 486: Difference between revisions
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== Structure == | == Structure == | ||
Diphtheria toxin is a protein made of 535 amino acids and is 58kDa in weight. The [http://en.wikipedia.org/wiki/Zymogen proenzyme](zymogen) must be cleaved into fragments A & B in order for the toxicity gene to be turn on. | Diphtheria toxin is a protein made of 535 amino acids and is 58kDa in weight. The [http://en.wikipedia.org/wiki/Zymogen proenzyme](zymogen) must be cleaved into fragments A & B in order for the toxicity gene to be turn on. In each fragment there are two <scene name='Sandbox_Reserved_486/Disulfide_bonds/1'>Disulfide Bonds</scene>. There are also three domains C,T, and R that have different functions. | ||
*<scene name='Sandbox_Reserved_486/Fragment_a/1'>Fragment A</scene> | |||
<scene name='Sandbox_Reserved_486/Ligands/2'>Ligand</scene> | <scene name='Sandbox_Reserved_486/Ligands/2'>Ligand</scene> | ||
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<scene name='Sandbox_Reserved_486/N_to_c_polymer/1'>N domain to C domain in the main chains</scene> | <scene name='Sandbox_Reserved_486/N_to_c_polymer/1'>N domain to C domain in the main chains</scene> | ||
<scene name='Sandbox_Reserved_486/Fragment_b/1'>Fragment B</scene> | <scene name='Sandbox_Reserved_486/Fragment_b/1'>Fragment B</scene> | ||
<scene name='Sandbox_Reserved_486/Active_site/1'>Active site</scene> | <scene name='Sandbox_Reserved_486/Active_site/1'>Active site</scene> | ||
