Sandbox Reserved 452: Difference between revisions
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== Structure == | == Structure == | ||
The c-myc protein contains two specific regions that characterize them as transcription factors: a carboxy-terminal basix helix-loop-helix leucine zipper motif and an amino terminal transactivation domain<ref>PMID:8193530</ref>. Immediatley following the basic region within the c-myc protein is the helix -loop-helix motif which has been shown to interact with DNA through binding <ref>PMID:8193530</ref>. The c-myc gene is essientially found on human chromosome 8q24 and contains three exons. | Secondary Structures | ||
The c-myc protein contains two specific regions that characterize them as transcription factors: a carboxy-terminal basix helix-loop-helix leucine zipper (bHLH-LZ) motif and an amino terminal transactivation domain<ref>PMID:8193530</ref>. The N-terminal domain functions in the activation of transcription, and the C-terminal, which contains the bHLH-LZ functions in Immediatley following the basic region within the c-myc protein is the helix -loop-helix motif which has been shown to interact with DNA through binding <ref>PMID:8193530</ref>. The c-myc gene is essientially found on human chromosome 8q24 and contains three exons. | |||
<Structure load='1A93' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | <Structure load='1A93' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> | ||
