Sandbox Reserved 490: Difference between revisions
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The DNA sequence that the dimerized estrogen receptor binds to is a palindromic sequence. This reflects the symmetric dimerization of the protein. | The DNA sequence that the dimerized estrogen receptor binds to is a palindromic sequence. This reflects the symmetric dimerization of the protein. | ||
This structure was determined using X-Ray Crystallography. | This structure was determined using X-Ray Crystallography. | ||
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The ligand used to determine this structure was estradiol, which is the physiologically appropriate ligand. Estradiol, or estrogen, has the following structure: | The ligand used to determine this structure was estradiol, which is the physiologically appropriate ligand. Estradiol, or estrogen, has the following structure: | ||
[[Image:http://content.answcdn.com/main/content/img/oxford/oxfordBiochemistry/0198529171.17b-estradiol.1.jpg | [[Image:http://content.answcdn.com/main/content/img/oxford/oxfordBiochemistry/0198529171.17b-estradiol.1.jpg]] | ||
