2wvj: Difference between revisions

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{{STRUCTURE_2wvj|  PDB=2wvj  |  SCENE=  }}  
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===MUTATION OF THR163 TO SER IN HUMAN THYMIDINE KINASE SHIFTS THE SPECIFICITY FROM THYMIDINE TOWARDS THE NUCLEOSIDE ANALOGUE AZIDOTHYMIDINE===
===Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine===


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==About this Structure==
==About this Structure==
2WVJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVJ OCA].  
[[2wvj]] is a 8 chain structure of [[Thymidine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVJ OCA].  
 
==See Also==
*[[Thymidine kinase|Thymidine kinase]]
 
==Reference==
<ref group="xtra">PMID:022385435</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thymidine kinase]]
[[Category: Thymidine kinase]]
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[[Category: Uhlin, U.]]
[[Category: Uhlin, U.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Cytoplasm]]
[[Category: Deoxyribonucleoside kinase]]
[[Category: Deoxyribonucleoside kinase]]
[[Category: Dna synthesis]]
[[Category: Dna synthesis]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Zinc-binding domain]]
[[Category: Zinc-binding domain]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 13:44:16 2009''

Revision as of 18:16, 2 May 2012

File:2wvj.png

Template:STRUCTURE 2wvj

Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine towards the Nucleoside Analogue Azidothymidine

Template:ABSTRACT PUBMED 22385435

About this Structure

2wvj is a 8 chain structure of Thymidine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Skovgaard T, Uhlin U, Munch-Petersen B. Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1. FEBS J. 2012 May;279(10):1777-87. doi: 10.1111/j.1742-4658.2012.08554.x. Epub, 2012 Mar 21. PMID:22385435 doi:10.1111/j.1742-4658.2012.08554.x

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