Sandbox Reserved 477: Difference between revisions

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NAD+ is the most common <scene name='Sandbox_Reserved_477/Ligand/1'>ligand</scene> for the binding of GAPDH. A ligand is a molecule that binds to a central atom to form a complex. NAD+ expresses negative cooperativity in relation to GAPDH; as NAD+ binds to the protein, the protein's affinity for the ligand decreases.
NAD+ is the most common <scene name='Sandbox_Reserved_477/Ligand/1'>ligand</scene> for the binding of GAPDH. A ligand is a molecule that binds to a central atom to form a complex. NAD+ expresses negative cooperativity in relation to GAPDH; as NAD+ binds to the protein, the protein's affinity for the ligand decreases.


<scene name='Sandbox_Reserved_477/Hydrophobic_residues/1'>hydrophobic residues</scene>
Due this enzyme's high content of <scene name='Sandbox_Reserved_477/Hydrophobic_residues/1'>hydrophobic residues</scene>, GAPDH maintains efficient stability by numerous hydrophobic interactions within the molecule.


[[Image:DomainAlisha.png| NAD Binding Domain | left | thumb | 300px]]
[[Image:DomainAlisha.png| NAD Binding Domain | left | thumb | 300px]]