User:Marvin O'Neal/OspA: Difference between revisions

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<h2>OspA Vaccination</h2>
<h2>OspA Vaccination</h2>


<Structure load="1fj1" size="350" frame="true" align="right" name="complex" caption="Outer surface protein A (OspA) in complex with the LA-2 Fab antibody ([[1fj1|1FJ1]])." scene="Studio:G2SecL03/Ospafab-orig/1"/>
<Structure load="1fj1" size="350" frame="true" align="right" name="complex" caption="Outer surface protein A (OspA) in complex with the LA-2 Fab antibody ([[1fj1|1FJ1]])." scene="Studio:G2SecL03/Ospafab-orig/2"/>


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<p>


To address this problem of international protection it would be helpful to create a chimera, mixing the OspA of different species. In order to do this the epitope of OspA should be studied. <scene name='Studio:G2SecL03/Ospafab-fab/1' target="complex">LA-2</scene> is a murine monoclonal antibody that <scene name='Studio:G2SecL03/Ospafab-interaction/1' target="complex">binds strongly</scene> to <scene name='Studio:G2SecL03/Ospafab-ospa/1' target="complex">OspA</scene>, and how effective a vaccine is correlated with LA-2 binding. 5
To address this problem of international protection it would be helpful to create a chimera, mixing the OspA of different species. In order to do this the epitope of OspA should be studied. <scene name='Studio:G2SecL03/Ospafab-fab/2' target="complex">LA-2</scene> is a murine monoclonal antibody that <scene name='Studio:G2SecL03/Ospafab-interaction/2' target="complex">binds strongly</scene> to <scene name='Studio:G2SecL03/Ospafab-ospa/2' target="complex">OspA</scene>, and how effective a vaccine is correlated with LA-2 binding. 5


<scene name='Studio:G2SecL03/Ospafab-orig/2' target="complex">Reset model</scene>
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<h3>Reference List of Available Scenes for OspA</h3>
<h3>List of Available Scenes for OspA</h3>
<ul>
<ul>
     <li><scene name='Studio:G2SecL03/Ospa_3loopscartoon/3' target="OspA-manip">Reset model</scene><br><br></li>
     <li><scene name='Studio:G2SecL03/Ospa_3loopscartoon/3' target="OspA-manip">Reset model</scene><br><br></li>