Sandbox Reserved 508: Difference between revisions
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2. A neutral fatty acid is flipped through the mitochondrial membrane into the matrix, and because of the basic environment, it releases the proton (H+). The now negatively charged anion is then transported | 2. A neutral fatty acid is flipped through the mitochondrial membrane into the matrix, and because of the basic environment, it releases the proton (H+). The now negatively charged anion is then transported | ||
through the membrane by UCP2.]] | through the membrane by UCP2.]] | ||
[[Image:BCSMART_11-12_Figure_5.JPG|left|375px|thumb|'''FIGURE 5: UCP2 Protein Structure''' | |||
<br> | |||
UCP2 is an inner mitochondrial membrane protein consisting of 6 transmembrane helices, shown in | |||
orange, with both the N- and C- termini pointing to the inter membrane space. UCP2 activity is inhibited | |||
by nucleotide binding (eg. GDP). Lys141 and Arg185, which are speculated to bind to GDP, are | |||
shown in light sky blue.]] | |||
