2h51: Difference between revisions
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[[Image:2h51.png|left|200px]] | [[Image:2h51.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
[[2h51]] is a 3 chain structure of [[Caspase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H51 OCA]. | |||
==See Also== | |||
*[[Caspase|Caspase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018590738</ref><ref group="xtra">PMID:016781734</ref><references group="xtra"/> | ||
[[Category: Caspase-1]] | [[Category: Caspase-1]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Wells, J A.]] | [[Category: Wells, J A.]] | ||
[[Category: Allosteric site]] | [[Category: Allosteric site]] | ||
[[Category: Dimer interface]] | [[Category: Dimer interface]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
Revision as of 05:06, 30 May 2012
Crystal structure of human caspase-1 (Glu390->Asp and Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Template:ABSTRACT PUBMED 18590738
About this Structure
2h51 is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Datta D, Scheer JM, Romanowski MJ, Wells JA. An allosteric circuit in caspase-1. J Mol Biol. 2008 Sep 19;381(5):1157-67. Epub 2008 Jun 20. PMID:18590738 doi:10.1016/j.jmb.2008.06.040
- Fang B, Boross PI, Tozser J, Weber IT. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360(3):654-66. Epub 2006 Jun 2. PMID:16781734 doi:10.1016/j.jmb.2006.05.041
