1pjr: Difference between revisions

Revision as of 13:19, 5 June 2012

Gene:

PCRA (Geobacillus stearothermophilus)

Structural annotation:
Resources:	CATH : 1Pjr001, 1Pjr002, 1Pjr004, 1Pjr003 InterPro : Ipr000212, Ipr014017, Ipr014016, Ipr005751 Pfam : PF00580 SCOP : d1pjr_2, d1pjr_1 UniProt : P56255

Functional annotation:
Cellular component:	cytoplasm
Biological process:	DNA repair DNA unwinding during replication
Molecular function:	ATP-dependent DNA helicase activity nucleotide binding ATP binding hydrolase activity helicase activity DNA binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1pjr is a 1 chain structure of Helicase with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Subramanya HS, Bird LE, Brannigan JA, Wigley DB. Crystal structure of a DExx box DNA helicase. Nature. 1996 Nov 28;384(6607):379-83. PMID:8934527 doi:10.1038/384379a0
Hicks JM, Hsu VL. The extended left-handed helix: a simple nucleic acid-binding motif. Proteins. 2004 May 1;55(2):330-8. PMID:15048824 doi:10.1002/prot.10630
Frick DN, Rypma RS, Lam AM, Frenz CM. Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations. Nucleic Acids Res. 2004 Oct 12;32(18):5519-28. Print 2004. PMID:15479787 doi:10.1093/nar/gkh891

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