DNA polymerase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 15: | Line 15: | ||
== 3D Structures of DNA polymerase == | == 3D Structures of DNA polymerase == | ||
''Updated | ''Updated June 2012'' | ||
===Family A – replicative and repair Dpo=== | ===Family A – replicative and repair Dpo=== | ||
| Line 37: | Line 37: | ||
[[3po4]], [[3po5]] - TaDpo I klenow fragment + DNA<br /> | [[3po4]], [[3po5]] - TaDpo I klenow fragment + DNA<br /> | ||
[[3py8]] - TaDpo I klenow fragment (mutant) + DNA<br /> | [[3py8]] - TaDpo I klenow fragment (mutant) + DNA<br /> | ||
[[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]] - TaDpo I klenow fragment + DNA + nucleotide<br /> | [[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]], [[3rr7]], [[3rr8]], [[3rrg]], [[3rrh]], [[3t3f]], [[4df4]], [[4df8]], [[4dfj]], [[4dfk]], [[4dfm]], [[4dfp]]- TaDpo I klenow fragment + DNA + nucleotide<br /> | ||
[[1xwl]] - GsDpo I fragment - ''Geobacillus stearothermophilus''<br /> | [[1xwl]] - GsDpo I fragment - ''Geobacillus stearothermophilus''<br /> | ||
[[2xo7]], [[3hp6]], [[3hpo]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[1xc9]], [[1ua0]], [[1ua1]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1l3s]], [[2bdp]], [[4bdp]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]] - GsDpo I fragment + DNA<br /> | [[2xo7]], [[3hp6]], [[3hpo]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[1xc9]], [[1ua0]], [[1ua1]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1l3s]], [[2bdp]], [[4bdp]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]] - GsDpo I fragment + DNA<br /> | ||
[[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]] - GsDpo I fragment + DNA + nucleotide<br /> | [[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]] - GsDpo I fragment + DNA + nucleotide<br /> | ||
[[3ti0]] - GsDpo I fragment + DNA + nucleotide - ''Bacillus''<br /> | |||
[[3ikm]] - hDpo γ1+γ2 - human<br /> | [[3ikm]] - hDpo γ1+γ2 - human<br /> | ||
[[3ikl]], [[2g4c]] - hDpo γ2<br /> | [[3ikl]], [[2g4c]] - hDpo γ2<br /> | ||
| Line 54: | Line 55: | ||
[[3nci]], [[3lds]], [[3l8b]], [[3cq8]],[[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]] - EpDpo (mutant) + DNA<br /> | [[3nci]], [[3lds]], [[3l8b]], [[3cq8]],[[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]] - EpDpo (mutant) + DNA<br /> | ||
[[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[2ozs]], [[2p5g]], [[2dy4]], [[1q9x]], [[1q9y]], [[1ig9]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]]- EpDpo (mutant) + DNA + nucleotide<br /> | [[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[2ozs]], [[2p5g]], [[2dy4]], [[1q9x]], [[1q9y]], [[1ig9]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]]- EpDpo (mutant) + DNA + nucleotide<br /> | ||
[[1clq]] - EpDpo + DNA + nucleotide<br /> | [[1clq]], [[3iuq]] - EpDpo + DNA + nucleotide<br /> | ||
[[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]] - EpDpo (mutant) + DNA + nucleotide analog<br /> | [[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]], [[3qei]], [[3qer]], [[3qes]], [[3qet]], [[3qev]], [[3qew]], [[3qex]], [[3qnn]], [[3qno]]- EpDpo (mutant) + DNA + nucleotide analog<br /> | ||
[[2atq]] – EpDpo + GP32<br /> | [[2atq]] – EpDpo + GP32<br /> | ||
[[1noy]] – T4Dpo + DNA - Enterobacteria phage T4<br /> | [[1noy]] – T4Dpo + DNA - Enterobacteria phage T4<br /> | ||
| Line 66: | Line 67: | ||
[[1n5g]], [[1k0p]], [[1k18]] - hDpo α zinc finger domain- NMR<br /> | [[1n5g]], [[1k0p]], [[1k18]] - hDpo α zinc finger domain- NMR<br /> | ||
[[1zqj]] – hDpo β + DNA<br /> | [[1zqj]] – hDpo β + DNA<br /> | ||
[[3rje]], [[3rjf]], [[3rjg]], [[3rjh]], [[3rji]], [[3rjj]], [[3rjk]], [[3tfr]], [[3tfs]] - hDpo β + nucleotide + DNA<br /> | |||
[[3e0j]] - hDpo δ2+δ3<br /> | [[3e0j]] - hDpo δ2+δ3<br /> | ||
[[3mr4]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]] - hDpo ε catalytic core + DNA + nucleotide<br /> | [[3mr4]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]] - hDpo ε catalytic core + DNA + nucleotide<br /> | ||
[[3tq1]] - hDpo η catalytic core + DNA<br /> | |||
[[4dl2]], [[4dl3]], [[4dl4]], [[4dl5]], [[4dl6]], [[4dl7]], [[4eey]] - hDpo η + DNA + nucleotide<br /> | |||
[[3oiq]] - yDpo α + cell division control protein 13 – yeast<br /> | [[3oiq]] - yDpo α + cell division control protein 13 – yeast<br /> | ||
[[3flo]], [[3lgb]] - yDpo α subunits A,B<br /> | [[3flo]], [[3lgb]] - yDpo α subunits A,B<br /> | ||
| Line 79: | Line 83: | ||
[[3k5o]], [[1q8i]] - EcDpo II (mutant)<br /> | [[3k5o]], [[1q8i]] - EcDpo II (mutant)<br /> | ||
[[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br /> | [[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br /> | ||
[[2jgu]] - PfDpo<br /> | [[2jgu]], [[4ahc]] - PfDpo<br /> | ||
[[4ail]] – PfDpo + DNA<br /> | |||
[[1tgo]] - TgDpo – ''Thermococcus gorgonarius''<br /> | [[1tgo]] - TgDpo – ''Thermococcus gorgonarius''<br /> | ||
[[2vwj]] – TgDpo (mutant) + DNA <br /> | [[2vwj]] – TgDpo (mutant) + DNA <br /> | ||
| Line 146: | Line 151: | ||
[[1kdh]] - mTdT+ nucleotide + DNA<br /> | [[1kdh]] - mTdT+ nucleotide + DNA<br /> | ||
[[2w9m]] – Dpo X – ''Deinococcus radiodurans''<br /> | [[2w9m]] – Dpo X – ''Deinococcus radiodurans''<br /> | ||
[[3au2]] – TtDpo β + GTP – ''Thermus thermophilus''<br /> | |||
[[3b0x]], [[3b0y]] – TtDpo β (mutant) + GTP<br /> | |||
[[3au6]], [[3auo]] – TtDpo β + GTP + DNA | |||
===Family Y – translesion Dpo=== | ===Family Y – translesion Dpo=== | ||
| Line 161: | Line 169: | ||
[[1t94]] - hDpo κ<br /> | [[1t94]] - hDpo κ<br /> | ||
[[3in5]] - hDpo κ + DNA<br /> | [[3in5]] - hDpo κ + DNA<br /> | ||
[[2w7o]], [[2w7p]], [[2oh2]] - hDpo κ + DNA + nucleotide<br /> | [[2w7o]], [[2w7p]], [[2oh2]], [[3pzp]] - hDpo κ + DNA + nucleotide<br /> | ||
[[2kwu]], [[2kwv]] - mDpo τ C-terminal + ubiquitin - NMR<br /> | [[2kwu]], [[2kwv]] - mDpo τ C-terminal + ubiquitin - NMR<br /> | ||
[[3ai4]] - mDpo τ/yEGFP<br /> | [[3ai4]] - mDpo τ/yEGFP<br /> | ||
| Line 168: | Line 176: | ||
[[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]] - SsDpo IV (mutant) + DNA + nucleotide<br /> | [[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]] - SsDpo IV (mutant) + DNA + nucleotide<br /> | ||
[[2xc9]], [[3m9m]], [[3m9n]], [[3m9o]], [[2v4q]], [[2v4r]], [[2ago]], [[1ryr]], [[1rys]], [[2w9a]], [[2w9b]], [[2w9c]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3qz7]], [[3qz8]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]]- SsDpo IV + DNA<br /> | [[2xc9]], [[3m9m]], [[3m9n]], [[3m9o]], [[2v4q]], [[2v4r]], [[2ago]], [[1ryr]], [[1rys]], [[2w9a]], [[2w9b]], [[2w9c]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3qz7]], [[3qz8]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]]- SsDpo IV + DNA<br /> | ||
[[2xca]], [[2xcp]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]] - SsDpo IV + DNA + nucleotide<br /> | [[2xca]], [[2xcp]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]], [[3t5h]], [[3t5j]], [[3t5k]], [[3t5l]], [[3v6h]], [[3v6j]], [[3v6k]] - SsDpo IV + DNA + nucleotide<br /> | ||
[[3fds]] – SsDpo IV + PCNA B + PCNA C<br /> | [[3fds]] – SsDpo IV + PCNA B + PCNA C<br /> | ||
[[3bq2]] – SaDpo IV + DNA – ''Sulfolobus acidocaldarius''<br /> | [[3bq2]] – SaDpo IV + DNA – ''Sulfolobus acidocaldarius''<br /> | ||
| Line 177: | Line 185: | ||
[[1s5j]] – SsDpo I<br /> | [[1s5j]] – SsDpo I<br /> | ||
[[3eyz]] - | [[3eyz]] - GsDpo I (mutant) + DNA <br /> | ||
[[3ez5]] - | [[3ez5]] - GsDpo I (mutant) + DNA + nucleotide <br /> | ||
[[3pv8]], [[3px0]], [[3px4]], [[3px6]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus'' | [[3pv8]], [[3px0]], [[3px4]], [[3px6]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus'' | ||
| Line 201: | Line 209: | ||
[[2keq]] - Dpo III α subunit – ''Nostoc punctiforme''<br /> | [[2keq]] - Dpo III α subunit – ''Nostoc punctiforme''<br /> | ||
[[3d1f]] - EcDpo III β subunit + polypeptide<br /> | [[3d1f]] - EcDpo III β subunit + polypeptide<br /> | ||
[[3p16]] - Dpo III β subunit – ''Mycobacterrium tuberculosis'' | [[3p16]], [[3rb9]] - Dpo III β subunit – ''Mycobacterrium tuberculosis''<br /> | ||
[[3q4j]], [[3q4k]], [[3q4l]] - EcDpo III β subunit + peptide | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
