CED-4 Apoptosome: Difference between revisions
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<StructureSection load="3lqq" size="400" color="" frame="true" spin="on" Scene='3lqq/Default/1' align="right" caption= > | |||
[[Image:3lqq.jpg|left|200px]] | [[Image:3lqq.jpg|left|200px]] | ||
===Structure of the CED-4 Apoptosome ([[3lqq]])=== | |||
===Structure of the CED-4 Apoptosome=== | |||
{{ABSTRACT_PUBMED_20434985}} | {{ABSTRACT_PUBMED_20434985}} | ||
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==About this Structure== | ==About this Structure== | ||
[[3lqq]] is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQQ OCA]. | |||
<scene name='3lqq/Default/1'>The crystallographic asymmetric unit of the solved structure is an asymmetric dimer</scene> of CED-4. <scene name='3lqq/Morph/2'>Morph showing how each monomer in the asymmetric dimer relate to each other</scene>. Be sure to spin it around because <scene name='3lqq/Morphside/3'>from the side it is easier to see the dramatic difference</scene>.<br> {{Button Toggle AnimationOnPause}}<!--When Proteopedia updates to a version of Jmol that supports the Compare command, I should upload a new pdb file with chain as a model and chain b as a model in a single pdb file and then replace this scene with a scripted compare that just compares model 2 (chain b) to model 1 (chain a).--> | <scene name='3lqq/Default/1'>The crystallographic asymmetric unit of the solved structure is an asymmetric dimer</scene> of CED-4. <scene name='3lqq/Morph/2'>Morph showing how each monomer in the asymmetric dimer relate to each other</scene>. Be sure to spin it around because <scene name='3lqq/Morphside/3'>from the side it is easier to see the dramatic difference</scene>.<br> {{Button Toggle AnimationOnPause}}<!--When Proteopedia updates to a version of Jmol that supports the Compare command, I should upload a new pdb file with chain as a model and chain b as a model in a single pdb file and then replace this scene with a scripted compare that just compares model 2 (chain b) to model 1 (chain a).--> | ||
<scene name='3lqq/Biomolecule1/4'>The biological molecule is an octamer (tetramer of the asymmetric dimer)</scene> that forms a shape similar to a funnel.<br> | <scene name='3lqq/Biomolecule1/4'>The biological molecule is an octamer (tetramer of the asymmetric dimer)</scene> that forms a shape similar to a funnel.<br> | ||
==External Links== | ==External Links== | ||
* [http://www.nature.com/nchina/2010/100707/full/nchina.2010.77.html '''Structural biology: The funnel of death''' by Felix Cheung] at Nature China. | * [http://www.nature.com/nchina/2010/100707/full/nchina.2010.77.html '''Structural biology: The funnel of death''' by Felix Cheung] at Nature China. | ||
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[[Category: Mitochondrion]] | [[Category: Mitochondrion]] | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
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Created with the participation of [[User:Wayne Decatur|Wayne Decatur]], [[User:Eran Hodis|Eran Hodis]]. | |||
