2w26: Difference between revisions
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Revision as of 06:50, 20 June 2012
Fator Xa in complex with BAY59-7939
Template:ABSTRACT PUBMED 16161994
About this Structure
2w26 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:16161994 doi:10.1021/jm050101d
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Lampe, T.
- Pernerstorfer, J.
- Perzborn, E.
- Pohlmann, J.
- Reinemer, P.
- Roehrig, S.
- Schaefer, M.
- Schlemmer, K.
- Straub, A.
- Blood coagulation
- Cleavage on pair of basic residue
- Egf-like domain
- Factor xa
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Protease
- Secreted
- Serine protease
- Zymogen
