3t5u: Difference between revisions

Revision as of 07:52, 20 June 2012

3t5u is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Di Fiore A, Maresca A, Alterio V, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem Commun (Camb). 2011 Nov 14;47(42):11636-8. Epub 2011 Sep 26. PMID:21952494 doi:10.1039/c1cc14575d
Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:https://dx.doi.org/10.1002/prot.340040406
Scott AD, Phillips C, Alex A, Flocco M, Bent A, Randall A, O'Brien R, Damian L, Jones LH. Thermodynamic optimisation in drug discovery: a case study using carbonic anhydrase inhibitors. ChemMedChem. 2009 Dec;4(12):1985-9. PMID:19882701 doi:10.1002/cmdc.200900386

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:3t5u.jpg|left|200px]]
-The entry 3t5u is ON HOLD  until Paper Publication
+{{STRUCTURE_3t5u|  PDB=3t5u  |  SCENE=  }}
-Authors: Di Fiore, A., Maresca, A., Alterio, V., Supuran, C.T., De Simone, G.
+===Crystal structure of the human carbonic anhydrase II in complex with N-hydroxy benzenesulfonamide===
-Description: Crystal structure of the human carbonic anhydrase II in complex with N-hydroxy benzenesulfonamide
+{{ABSTRACT_PUBMED_21952494}}
+==About this Structure==
+[[3t5u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5U OCA].
+==Reference==
+<ref group="xtra">PMID:021952494</ref><ref group="xtra">PMID:003151019</ref><ref group="xtra">PMID:019882701</ref><references group="xtra"/>
+[[Category: Carbonate dehydratase]]
+[[Category: Homo sapiens]]
+[[Category: Alterio, V.]]
+[[Category: Fiore, A Di.]]
+[[Category: Maresca, A.]]
+[[Category: Simone, G De.]]
+[[Category: Supuran, C T.]]
+[[Category: Lyase-lyase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]