4dum: Difference between revisions

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[[Image:4dum.png|left|200px]]
[[Image:4dum.png|left|200px]]


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===Co-crystal structure of eIF4E with inhibitor===
===Co-crystal structure of eIF4E with inhibitor===


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{{ABSTRACT_PUBMED_22458568}}
{{ABSTRACT_PUBMED_22458568}}


Revision as of 04:41, 27 June 2012

File:4dum.png

Template:STRUCTURE 4dum

Co-crystal structure of eIF4E with inhibitor

Template:ABSTRACT PUBMED 22458568

About this Structure

4dum is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chen X, Kopecky D, Mihalic J, Jeffries S, Min X, Heath J, Deignan J, Sujen L, Fu Z, Guimaraes C, Li S, Johnstone S, Xu H, Cardozo M, Shen W, Walker N, Kayser F, Wang Z. Structure-guided design, synthesis and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction. J Med Chem. 2012 Mar 29. PMID:22458568 doi:10.1021/jm300037x

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