4fod: Difference between revisions
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[[Image:4fod.jpg|left|200px]] | |||
{{STRUCTURE_4fod| PDB=4fod | SCENE= }} | |||
===Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36=== | |||
{{ABSTRACT_PUBMED_22734674}} | |||
==About this Structure== | |||
[[4fod]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOD OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022734674</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Receptor protein-tyrosine kinase]] | |||
[[Category: Chen, H.]] | |||
[[Category: Epstein, L F.]] | |||
[[Category: Whittington, D A.]] | |||
[[Category: Cd246]] | |||
[[Category: Crizotinib]] | |||
[[Category: Eml4-alk]] | |||
[[Category: Inhibitor]] | |||
[[Category: Neuroblastoma]] | |||
[[Category: Npm-alk]] | |||
[[Category: Phosphotransferase]] | |||
[[Category: Receptor tyrosine kinase]] | |||
[[Category: Transferase-inhibitor complex]] | |||
Revision as of 08:10, 11 July 2012
Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36
Template:ABSTRACT PUBMED 22734674
About this Structure
4fod is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lewis RT, Bode CM, Choquette D, Potashman M, Romero K, Stellwagen JC, Teffera Y, Moore E, Whittington DA, Chen H, Epstein LF, Emkey R, Andrews PS, Yu V, Saffran DC, Xu M, Drew AE, Merkel P, Szilvassy S, Brake RL. The discovery and optimization of a novel class of potent, selective and orally bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with potential utility for the treatment of cancer. J Med Chem. 2012 Jun 26. PMID:22734674 doi:10.1021/jm3005866
