4dpf: Difference between revisions
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[[Image:4dpf.jpg|left|200px]] | |||
{{STRUCTURE_4dpf| PDB=4dpf | SCENE= }} | |||
===BACE-1 in complex with a HEA-macrocyclic type inhibitor=== | |||
{{ABSTRACT_PUBMED_22698785}} | |||
==About this Structure== | |||
[[4dpf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DPF OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022698785</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Memapsin 2]] | |||
[[Category: Borkakoti, N.]] | |||
[[Category: Derbyshire, D.]] | |||
[[Category: Lindberg, J.]] | |||
[[Category: Asp2]] | |||
[[Category: Bace]] | |||
[[Category: Bace1]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Macrocycle]] | |||
Revision as of 08:12, 11 July 2012
BACE-1 in complex with a HEA-macrocyclic type inhibitor
Template:ABSTRACT PUBMED 22698785
About this Structure
4dpf is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sandgren V, Agback T, Johansson PO, Lindberg J, Kvarnstrom I, Samuelsson B, Belda O, Dahlgren A. Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: Design, synthesis and X-ray crystal structures of enzyme inhibitor complexes. Bioorg Med Chem. 2012 Jul 15;20(14):4377-89. Epub 2012 May 24. PMID:22698785 doi:10.1016/j.bmc.2012.05.039
