190d: Difference between revisions

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New page: left|200px<br /><applet load="190d" size="450" color="white" frame="true" align="right" spinBox="true" caption="190d, resolution 1.800Å" /> '''CRYSTAL STRUCTURE O...
 
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[[Image:190d.gif|left|200px]]<br /><applet load="190d" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:190d.gif|left|200px]]<br /><applet load="190d" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="190d, resolution 1.800&Aring;" />
caption="190d, resolution 1.800&Aring;" />
'''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)'''<br />
'''CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)'''<br />


==Overview==
==Overview==
The crystal structure of d(C4) solved at 2.3-A resolution reveals a, four-stranded molecule composed of two interdigitated or intercalated, duplexes. The duplexes are held together by hemiprotonated, cytosine-cytosine base pairs and are parallel stranded, but the two, duplexes point in opposite directions. The molecule has a slow, right-handed twist of 12.4 degrees between covalently linked cytosine base, pairs, and the base stacking distance is 3.1 A. This is in general, agreement with the NMR studies. A biological role for DNA in this, conformation is suggested.
The crystal structure of d(C4) solved at 2.3-A resolution reveals a four-stranded molecule composed of two interdigitated or intercalated duplexes. The duplexes are held together by hemiprotonated cytosine-cytosine base pairs and are parallel stranded, but the two duplexes point in opposite directions. The molecule has a slow right-handed twist of 12.4 degrees between covalently linked cytosine base pairs, and the base stacking distance is 3.1 A. This is in general agreement with the NMR studies. A biological role for DNA in this conformation is suggested.


==About this Structure==
==About this Structure==
190D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=190D OCA].  
190D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=190D OCA].  


==Reference==
==Reference==
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[[Category: u-dna]]
[[Category: u-dna]]


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